Challenges in Measuring Glomerular Filtration Rate: A Clinical Laboratory Perspective
نویسندگان
چکیده
منابع مشابه
Using glomerular filtration rate estimating equations: clinical and laboratory considerations.
Glomerular filtration rate (GFR) estimating equations, infrequently used just a decade ago, are now recommended for the evaluation of kidney function for routine clinical care and are routinely reported by the vast majority of clinical laboratories (1 ). Current clinical guidelines recommend estimated GFR (eGFR) based on serum creatinine (eGFRCr) as the initial diagnostic test, and either a mea...
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A technique for measuring glomerular filtration rate (by six-sample plasma clearance) and extracellular fluid volume is described. The results obtained for glomerular filtration rat per extracellular fluid volume with a three blood sample technique are also presented. Concurrently with the blood sample techniques measuring plasma clearance, glomerular filtration rate per extracellular fluid vol...
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A method for estimating glomerular filtration rate (GFR) has been developed that is based on an analysis of the total area under the plasma radioactivity-time curve after a single intravenous injection of [125I]iothalamate. Glomerular filtration rates obtained by this method (method A) and those obtained with two widely used single-injection techniques, the slope-intercept method (method B), a...
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OBJECTIVE The purpose of this study was to develop a simpler method to measure severely reduced glomerular filtration rate (GFR) for patients with a GFR below 30 mL/min. METHOD The GFR was measured in 24 patients using both the 51Cr EDTA slope-intercept method (the conventional method) and 99mTc-DTPA with our proposed simpler GFRn method. RESULTS The correlation coefficient was 0.92 between...
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ژورنال
عنوان ژورنال: Advances in Chronic Kidney Disease
سال: 2018
ISSN: 1548-5595
DOI: 10.1053/j.ackd.2017.10.006